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YWHAE, Recombinant, Human, aa1-255, His-Tag (14-3-3 Protein epsilon, 14-3-3E, HEL2, KCIP-1, MDCR, MDS) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | YWHAE, Recombinant, Human, aa1-255, His-Tag (14-3-3 Protein epsilon, 14-3-3E, HEL2, KCIP-1, MDCR, MDS) |
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| Description | Purity ~90% (SDS-PAGE). YWHAE, also known as 14-3-3 protein epsilon, is adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, delta, zeta, tau and eta that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron- specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Source: Recombinant protein corresponding to aa24-188 from human YWHAE, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~31.3kD (275aa), confirmed by MALDI-TOF Endotoxin: <1EU/1ug (determined by LAL method) AA |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_006752 |
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| Catalog # | 378010 |
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| Order / More Info | YWHAE, Recombinant, Human, aa1-255, His-Tag (14-3-3 Protein epsilon, 14-3-3E, HEL2, KCIP-1, MDCR, MDS) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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