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Antigenic Specificity | Interleukin 2 Receptor, alpha (IL2RA) |
Clone | 7D4 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgM |
Format | phycoerythrin (PE) conjugate |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. It is transiently expressed at a low level during B-cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus. |
Immunogen | IL-2-dependent BALB/c mouse helper T-cell clone HT-2 1 |
Other Names | CD25|HEM45|IDDM10|IL2R|TCGFR|IL2RAC|IL-2RA|Il2r|Ly-43 |
Gene, Accession # | Gene ID: 16184 |
Catalog # | ABIN135174 |
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Order / More Info | Interleukin 2 Receptor, alpha (IL2RA) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 1717581, 6412230 |
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