| 产品名称 |
Apolipoprotein, Recombinant, Human (A-I/ApoA1, Alp-1, APOA1, Brp-14, Ltw-1, Lvtw-1, Sep-1, Sep-2) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | Apolipoprotein, Recombinant, Human (A-I/ApoA1, Alp-1, APOA1, Brp-14, Ltw-1, Lvtw-1, Sep-1, Sep-2) |
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| Description | Purity >95% (SDS-PAGE). Apolipoprotein A1 (ApoA1) is a 28kD glycoprotein that is the major protein component of high density lipoprotein (HDL) particles. HDL particles play a central role in the reverse transport of cholesterol from peripheral tissues to the liver. HDL is known as ``good cholesterol'' due to its ability to facilitate the removal of cholesterol from macrophage foam cells in atherosclerotic plaques and thereby retard the progression of disease (1, 2). ApoA1 is secreted from hepatocytes with variable amounts of lipidation (3). Disclike HDL particles increase in size and adopt a spherical shape as they are loaded with additional lipids and cholesterol by ABC family transporters (4, 5). HDL particle interaction with lipidsupplying cells is mediated by ApoA1 binding to the scavenger receptor SR-A1 (6). HDL particles are further modified by the circulating enzymes LCAT (which converts cholesterol to cholesteryl esters), CETP (which transfers cholesteryl esters to LDL/VLDL par |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P02647 |
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| Catalog # | 167625 |
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| Price | |
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| Order / More Info | Apolipoprotein, Recombinant, Human (A-I/ApoA1, Alp-1, APOA1, Brp-14, Ltw-1, Lvtw-1, Sep-1, Sep-2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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