产品详情 |
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Antigenic Specificity | Interleukin 2 Receptor, alpha (IL2RA) |
Clone | 3C7 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b |
Format | Spectral Red (SPRD) conjugate |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity α chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. Expression of CD25 on activated T lymphocytes is transitory and endogenously regulated. CD25 is expressed on precursor B cells in bone marrow. Its expression is initiated by functional rearrangement and expression of IgM heavy chain genes and is down-regulated when immature B cells mature and express IgD. It is expressed at a higher level on CD4 + CD8 + thymocytes. It is also expressed on cultured epidermal Langerhans cells. The biochemical features of murine CD25 have been characterized in detail. |
Immunogen | n/a |
Other Names | CD25|HEM45|IDDM10|IL2R|TCGFR|IL2RAC|IL-2RA|Il2r|Ly-43 |
Gene, Accession # | Gene ID: 16184 |
Catalog # | ABIN375573 |
Price | |
Order / More Info | Interleukin 2 Receptor, alpha (IL2RA) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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