| 产品详情 |
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| Antigenic Specificity | KPNA1 |
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| Clone | 114-E12 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunofluorescence: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KPNA1 Monoclonal Antibody (114-E12). The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), whic |
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| Immunogen | n/a |
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| Other Names | Karyopherin A2, KPNA2, IMA2, Importin alpha 2, Importin alpha P1, Importin subunit alpha-2, IPOA1, IPOA 1, IPOA1, Karyopherin alpha 2 subunit, RAG cohort 1, RCH 1, RCH1, SRP 1, SRP1 alpha, SRP1 |
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| Gene, Accession # | Entrez: 16646, 3836; Uniprot: P52294, Q60960 |
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| Catalog # | 37-0800 |
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| Price | |
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| Order / More Info | KPNA1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21555516 |
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