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Antigenic Specificity | KPNA2 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: Assay-dependent, Immunofluorescence: Assay Dependent, peptide-ELISA: 1:32000, Western Blot: 0.03-0.1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KPNA2 Polyclonal Antibody. The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 , which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the |
Immunogen | n/a |
Other Names | KPNA2; IPOA1 QIP2; RCH1; SRP1alpha; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); RAG cohort 1; importin alpha 1; importin alpha 2; importin-alpha-P1; karyopherin alpha 2; pendulin |
Gene, Accession # | Entrez: 3838; Uniprot: P52292 |
Catalog # | PA5-18237 |
Price | |
Order / More Info | KPNA2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |