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| Antigenic Specificity | RAN Binding Protein 9 (RANBP9) |
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| Clone | 3C3-E11-C12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | affinity purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunocytochemistry (ICC),Immunoprecipitation (IP) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA. Subunit structure: Interacts with NGFR and DDX4. Interacts with GTP-bound Ran, AR, CDC2L1/p110C, CALB1, S100A7, USP11, MKLN1, SOS1 or SOS2, C20orf11, and FMR1. Interacts with the Dyrk kinases HIPK2, DYRK1A, and DYRK1B. Interacts with TP73 isoform Alpha but not with TP53. Interacts with the HGF receptor MET and the integrins ITGB1 and ITGB2, but not with ITGAL. Part of a complex consisting of RANBP9, MKLN1 and C20ORF11. Part of a complex consisting of RANBP9, RAN, DYRK1B and COPS5. Directly interacts with RANBP10. Subcellular location: Cytoplasm > cytosol. Nucleus. Sequence similarities: Belongs to the RANBP9/10 family. Contains 1 B30. 2/SPRY domain. Contains 1 CTLH domain. Contains 1 LisH domain. |
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| Immunogen | Purified recombinant human RanBP9 protein fragments expressed in E.coli. |
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| Other Names | RGD1561940|RanBPM|A330055O14Rik|C330016G14|Imp7|Ranbp7|CG5252|Dmel\\CG5252|RANBP9|bpm-l|bpm90|ranbp10|ranbpm|Ranbpm|BPM-L|BPM90|RANBPM|RanBP7|IBAP-1|Ibap1|cb457|zgc:158650|ranbp9|ranbp9a |
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| Gene, Accession # | Gene ID: 10048 |
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| Catalog # | ABIN1558189 |
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| Price | |
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| Order / More Info | RAN Binding Protein 9 (RANBP9) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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