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Antigenic Specificity | Karyopherin (Importin) beta 1 (KPNB1) |
Clone | 2501C3a |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 50 µg |
Concentration | n/a |
Applications | Dot Blot (DB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Synonyms: Monoclonal KPNB1 antibody, Anti-KPNB1 antibody, Karyopherin (importin) beta 1 antibody, IMB1 antibody, IPOB antibody, Impnb antibody, NTF97 antibody, MGC2155 antibody, MGC2156 antibody, MGC2157 antibody. |
Immunogen | KPNB1 antibody was raised in mouse using recombinant Human Karyopherin (Importin) Beta 1 (Kpnb1) |
Other Names | Afu1g15720|AO090005001133|imb1|impnb|ipo1|ipob|ntf97|IMB1|IPO1|IPOB|Impnb|NTF97|AA409963 |
Gene, Accession # | Gene ID: 3837 |
Catalog # | ABIN931028 |
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Order / More Info | Karyopherin (Importin) beta 1 (KPNB1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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