产品详情 |
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Antigenic Specificity | RCH1/KPNA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RCH1/KPNA2 Polyclonal Antibody. Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA2 is the alpha subunit 2 of karyopherin, which forms a complex with importin subunit beta-1 and functions as a cargo carrier that transports various complexes from cytoplasm into nucleus. It is ubiquitously expressed and contains an IBB/importin beta domain, ten Armadillo repeats that bind cargo and three intervening nucle |
Immunogen | n/a |
Other Names | IPOA1, QIP2, RCH1, SRP1alpha |
Gene, Accession # | Entrez: 16647, 3838; Uniprot: P52292, P52293 |
Catalog # | IHC-00201 |
Price | |
Order / More Info | RCH1/KPNA2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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