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Antigenic Specificity | O-linked N-acetylglucosamine (O-GlcNAc) |
Clone | HGAC85 |
Host Species | Mouse |
Reactive Species | all |
Isotype | IgG3 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay dependent, Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunoprecipitation: Assay dependent, Western Blot: 1:250-1:1,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | O-linked N-acetylglucosamine (O-GlcNAc) Monoclonal Antibody (HGAC85). Many cellular proteins, including nuclear pore, oncogene, cytoskeletal, heat shock, viral and transcription regulatory proteins contain single O-linked N-acetylglucosamine (O-GlcNAc) residues attached to serine or threonine residues. It has been observed that O-GlcNAc glycosylated proteins tend to be under phosphorylated relative to unglycosylated proteins and that O-GlcNAc bearing proteins tend to be found in multimeric complexes. This has led to the suggestion that O-GlcNAc glycosylation may obscure phosphorylation sites and acts as a signaling mechanism or mediator of signaling. |
Immunogen | n/a |
Other Names | GlcNAc |
Gene, Accession # | Entrez: 108155, 26295, 8473; Uniprot: O15294, P56558, Q8CGY8 |
Catalog # | MA1-076 |
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Order / More Info | O-linked N-acetylglucosamine (O-GlcNAc) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 11689440, 15161761, 17029291, 17403669, 18812238, 19776393, 20368426, 24573683, 26957542, 6180013 |
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