产品详情 |
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Antigenic Specificity | CSE1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CSE1 Polyclonal Antibody. Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]. |
Immunogen | n/a |
Other Names | CAS, CSE1, MGC117283, MGC130036, MGC130037, XPO2 |
Gene, Accession # | Entrez: 110750, 1434; Uniprot: P55060, Q9ERK4 |
Catalog # | IHC-00138 |
Price | |
Order / More Info | CSE1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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