产品详情 |
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Product Name | MK 217 |
Description | Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts. MW (observed): 271.08. |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | P,P'-(4-Amino-1-hydroxybutylidene)bis-phosphonic acid monosodium salt. Alendronate sodium |
Gene, Accession, CAS # | CAS: 129318-43-0 |
Catalog # | 4014/50 |
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Order / More Info | MK 217 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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