产品详情 |
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Antigenic Specificity | Propoxyphene |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | n/a |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA: 5-10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Propoxyphene Polyclonal Antibody. Propoxyphene is the d-isomer of synthetic diphenyl propionate derivative propoxyphene, with narcotic analgesic effect. This agent mimics the effects of the endogenous opiate dextropropoxyphene by binding to mu receptors located throughout the central nervous system. The binding results in GTP to GDP exchanges on the mu-G-protein complex, by which effector adenylate cyclase is inactivated, thereby decreasing intracellular cAMP. This inhibits the release of various nociceptive neurotransmitters such as substance P, gamma-aminobutyric acid (GABA), dopamine, acetylcholine, noradrenaline, vasopressin, and somatostatin. In addition, dextropropoxyphene closes N-type voltage-gated calcium channels and opens calcium |
Immunogen | n/a |
Other Names | Dextropropoxyphene; D-Propoxyphene; Dextropropoxyphen; Dextroproxifeno; Destropropossifene; C22H29NO2 |
Gene, Accession # | n/a |
Catalog # | PA1-75369 |
Price | |
Order / More Info | Propoxyphene Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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