产品详情 |
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Antigenic Specificity | TACR3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 50 ug |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 20 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TACR3 Polyclonal Antibody. The tachykinins are a family of small peptides that include the neurotransmitters substance P, neurokinin A, and neurokinin B, which can act on three related but distinct seven transmembrane G-proteins coupled receptors, albeit at different concentrations. The NK-3 receptor (NK3R) has greatest affinity for neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system. It is likely these signals lead to the release of vasopressin and oxytocin into the circulation. NK3R may be involved in learning and memory as mice lacking this gene expressed cognitive deficits compared to normal mice. Althoug |
Immunogen | n/a |
Other Names | TACR3, HH11, Nmk-r, NK3R, NKR, Tachykinin receptor 3, Neurokinin B, Neurokinin B receptor, NK-3 receptor, NK-3R, TAC3R, Neurokinin 3 receptor, Neurokinin beta receptor, Neuromedin-K receptor, TAC3RL |
Gene, Accession # | Entrez: 6870; Uniprot: P29371 |
Catalog # | PA5-34249 |
Price | |
Order / More Info | TACR3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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