| 产品详情 |
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| Product Name | SHP-1, Recombinant, Human |
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| Description | Purity ~95% (RP-HPLC, SDS-PAGE). SHP-1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. The catalytic domain of SHP-1 was overexpressed as insoluble protein aggregates (inclusion bodies). Source: Recombinant protein correspondi |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SHP-1, Recombinant, Human (Tyrosine-protein Phosphatase Non-receptor type 6, EC 3.1.3.48, Protein-tyrosine Phosphatase 1C, PTP-1C, Hematopoietic Cell Protein-tyrosine Phosphatase, SH- PTP1, Protein-tyrosine Phosphatase SHP-1, PTPN6, HCP, HCPH, SHP1, HPTP1C, SHP-1L) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209203 |
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| Order / More Info | SHP-1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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