| 产品详情 |
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| Product Name | Mps1-IN-1 |
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| Description | Purity >98%. Mps1-IN-1 is a selective inhibitor of monopolar spindle 1 (Mps1) kinase (IC50 = 367 nM), a dual-specificity kinase involved in spindle assembly checkpoint and the maintenance of chromosomal stability. It exhibits greater than 1,000-fold selectivity against a panel of 352 kinases. Mps1-IN-1 has been shown to disrupt the recruitment of Mad2 to kinetochores and to increase the frequency of multipolar mitosis in U2OS cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[3-methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol, Monopolar Spindle 1 Kinase Inhibitor 1, Mps1 Kinase Inhibitor 1 |
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| Gene, Accession, CAS # | CAS: 1125593-20-5 |
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| Catalog # | LS-H8810 |
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| Price | |
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| Order / More Info | Mps1-IN-1 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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