| 产品详情 |
| Edit |   |
|---|
| Product Name | F-Amidine (trifluoroacetate salt) |
|---|
| Description | Purity >95%. F-amidine is an inhibitor of protein arginine deiminases (PADs) that is selective for PAD1 and PAD4 (IC50 s = 29.5, 350, and 21.6 µM for PAD1, PAD3, and PAD4 in vitro, respectively). It irreversibly inactivates all four PAD subtypes (kinact /KI = 2,800, 380, 170, and 3,000 M-1 min-1 by covalently modifying an active site cysteine that is important for its catalytic activity. F-amidine is cytotoxic to HL-60, MCF-7, and HT-29 cancer cell lines (IC50 s = 0.5, 0.5 and 1 µM, respectively). |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | N-[(1S)-1-(aminocarbonyl)-4-[(2-fluoro-1-iminoethyl)amino]butyl]-benzamide, 2,2,2-trifluoroacetate |
|---|
| Gene, Accession, CAS # | CAS: 877617-46-4 |
|---|
| Catalog # | LS-H7751 |
|---|
| Price | |
|---|
| Order / More Info | F-Amidine (trifluoroacetate salt) from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|