产品名称 YES1, Recombinant, Human, GST-Tag (Proto-Oncogene Tyrosine Protein Kinase YES, Yes, c-yes, HsT441, P61-YES) from UNITED STATES BIOLOGICAL
产品货号 500551
产品价格 现货询价,电话:010-67529703
产品规格 10ug
产品品牌 UNITED STATES BIOLOGICAL
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Product NameYES1, Recombinant, Human, GST-Tag (Proto-Oncogene Tyrosine Protein Kinase YES, Yes, c-yes, HsT441, P61-YES)
DescriptionPurified (~70-90%). YES1 is the cellular homolog of the Yamaguchi sarcoma virus oncogene that has tyrosine kinase activity and belongs to the SRC family. YES1 lies in close proximity to thymidylate synthase gene on chromosome 18 and chromosome 22. The activation of YES1 may play a significant role in the malignant transformation of hepatocytes, and is important for maintaining embryonic stem cells in an undifferentiated state. YES1 is a useful marker to detect early-stage hepatocellular carcinoma, and it plays a key role in the tumorigenesis and metastasis of gastric cancer. YES1 induction results in increased cancer cell motility suggesting that YES1 may promote cancer spread and metastasis rather than tumor growth. Source: Recombinant protein corresponding to human YES1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~91kD Specific Activity: 185nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL)
Size10ug
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Gene, Accession, CAS #Accession: NM_005433, SwissProt: P07947
Catalog #500551
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Order / More InfoYES1, Recombinant, Human, GST-Tag (Proto-Oncogene Tyrosine Protein Kinase YES, Yes, c-yes, HsT441, P61-YES) from UNITED STATES BIOLOGICAL
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