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TK2, Recombinant, Human, aa34-265, His-Tag (Thymidine Kinase 2, Mitochondrial, MTDPS2, MTTK) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | TK2, Recombinant, Human, aa34-265, His-Tag (Thymidine Kinase 2, Mitochondrial, MTDPS2, MTTK) |
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| Description | Purity ~85% (SDS-PAGE). TK2, also known as thymidine kinase 2 mitochondrial, belongs to the DCK/DGK family. Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'- phosphotransferase, It can be found in most living cells. It is present in two forms in mammalian cells, TK1 and TK2. Certain viruses also have genetic information for expression of viral thymidine kinases. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Defects in TK2 are a cause of mitochondrial DNA depletion syndrome type 2 (MTDPS2). A disorder characterized primarily by childhood onset of muscle weakness associated with depletion of mtDNA in skeletal muscle. Source: Recombinant protein corresponding to aa34-265 from human TK2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~30.2kD (257aa) AA |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_004605 |
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| Catalog # | 351529 |
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| Order / More Info | TK2, Recombinant, Human, aa34-265, His-Tag (Thymidine Kinase 2, Mitochondrial, MTDPS2, MTTK) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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