产品详情 |
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Antigenic Specificity | RNF7 |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Sheep Anti-Human RNF7 polyclonal antibody for WB, IP. The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
Immunogen | human RNF7 (residues 1-113) [GST-tagged] |
Other Names | n/a |
Gene, Accession # | Gene ID: 9616, UniProt: Q9UBF6 |
Catalog # | CABT-BL6327 |
Price | |
Order / More Info | RNF7 Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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