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| Product Name | Glutamate Decarboxylase 67, Rat, Control Peptide (GAD67) |
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| Description | Highly purified. Control Peptide for G4000-12 (antiserum) and G4000-12D (affinity purified) An 18-aa peptide sequence near the amino terminus of mouse/rat GAD67 (1) was synthesized and coupled to KLH. g-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain. Glutamic acid decarboxylase (GAD; E.C.4.1.1.15) catalyzes the decarboxylation of glutamate to produce GABA-the rate limiting step in the synthesis of GABA. The two major isoform of GAD, GAD67 (MW 67kD) and GAD65 (MW 65kD) are derived from distinct genes and differ in their subcellular distribution. GAD67 is 594 aa single chain polypeptide encoded by human chromosome 2 gene, whereas GAD65 is am amphiphilic and membrane anchored protein (585 aa, chromosome 10). GAD isoform shares ~65% homology. GAD is also a major autoantigen associated with SMS (stiff-man syndrome). Applications: Suitable for use in ELISA and Antibody Blocking. Not suitable for use in Western Blot. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | G4000-12F |
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| Order / More Info | Glutamate Decarboxylase 67, Rat, Control Peptide (GAD67) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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