| 产品详情 |
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| Antigenic Specificity | tropomyosin, striated muscle |
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| Clone | CH1 |
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| Host Species | Mouse |
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| Reactive Species | axolotl, broad species, chicken, fish, human, mouse, rat, Xenopus |
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| Isotype | IgG1 |
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| Format | supernatant |
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| Size | 1.0 ml |
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| Concentration | n/a |
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| Applications | ELISA, FFPE, Function Blocking, Immunofluorescence, Immunoprecipitation, Western Blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Epitope: CH1 has been reported to bind to the peptide region encoded by exon 9a of TPM genes [PMID: 24958154]; this exon is well conserved in all vertebrates. But, the binding of CH1 has also been described to be limited to alpha9a [PMID: 22069507]. CH1 reacts strongly with striated muscle forms of tropomyosin, including cardiac alpha-tropomyosin and skeletal alpha- and beta-tropomyosins, but not with tropomyosin isoforms from gizzard (smooth muscle) or chicken embryo fibroblasts. CH1 interferes with the binding of tropomyosin to actin. CH1 recognizes sarcomeric Tm soforms alpha-fast, beta, and alpha-slow with poor affinity for alpha-slow. |
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| Immunogen | Purified chicken cardiac muscle tropomyosin: Full length protein |
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| Other Names | n/a |
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| Gene, Accession # | TPM1, Gene ID: 396366, UniProt: P04268 |
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| Catalog # | CH1 |
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| Price | |
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| Order / More Info | tropomyosin, striated muscle Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK |
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| Product Specific References | PubMed: 3899907, 15249230, 9853962, 26310270, 25952972, 27194630, 27081572, 25984327, 24633745, 2323957, 9662653, 10644411, 16107252, 15845393, 3899907, 26171250, 24958154, 26041514, 27553280, 26447205, 25984327, 8530495, 2668298, 23712688, 9621993, 26024675, 16981728, 27429059, 17260966, 3899907 |
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