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| Product Name | JTB, Recombinant, Human, aa31-105, His-Tag (Jumping Translocation Breakpoint) |
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| Description | Purity ~85% (SDS-PAGE). Jumping translocation breakpoint, also known as JTB, is required for normal cytokinesis during mitosis. This protein plays a role in the regulation of cell proliferation. This protein may be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. It lnhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential. Source: Recombinant protein corresponding to aa31-105 from human JTB, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~10.7kD (98aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_006685 |
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| Catalog # | 218280 |
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| Order / More Info | JTB, Recombinant, Human, aa31-105, His-Tag (Jumping Translocation Breakpoint) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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