| 产品详情 |
| Edit |   |
|---|
| Product Name | ANG-1, Recombinant, Human, His-Tag (Angiopoietin-1, ANGPT1) |
|---|
| Description | Purity ~95% (SDS-PAGE). Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a tyrosine-kinase receptor expressed primarily on vascular endothelial cells and early hematopoietic cells. Ang-1/Tie-2 signaling promotes angiogenesis during the development, remodeling, and repair of the vascular system. Transgenic mice lacking expression of either Ang-1 or Tie-2 fail to develop a fully functional cardiovascular system and die before birth. Postnatally, the angiogenic activity of Ang-1/Tie-2 is required during normal tissue repair and remodeling of the female endometrium in the menstrual cycle. Ang-1/Tie-2 signaling appears to be regulated by Angiopoietin-2 (Ang-2), a natural antagonist for Tie-2 that exerts its effects through an internal autocrine loop mechanism. In addition to suppressing endothelial cell activation by inhibiting the expression of adhesion and inflammatory molecules, Ang-1 enhances endothelial cell survival and capillary morphogenesis, and lessens capillary permeability |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Angiopoietin-1 |
|---|
| Gene, Accession, CAS # | ANGPT1, Gene ID: 284, SwissProt: Q15389 |
|---|
| Catalog # | 219373 |
|---|
| Price | |
|---|
| Order / More Info | ANG-1, Recombinant, Human, His-Tag (Angiopoietin-1, ANGPT1) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|