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| Product Name | MAPKAPK3, 1-382aa, Human, His tag, E Coli |
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| Description | MW: 45.4 kDa (405aa) confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. MAP kinase-activated protein kinase 3, also known as MAPKAPK3, is involved in inflammatory response by regulating tumor necrosis factor (TNF) and IL6 production post-transcriptionally: acts by phosphorylating Au-rich elements (AREs)-binding proteins, such as TTP/ZFP36, leading to regulate the stability and translation of TNF and IL6 mRNAs. Phosphorylation of TTP/ZFP36, a major post-transcriptional regulator of TNF, promotes it |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [MAP kinase-activated protein kinase 3; 3PK; MAPKAP-K3; MAPKAP3; MAPKAPK-3; MK-3] |
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| Gene, Accession, CAS # | MAPKAPK3, Gene ID: 7867, Accession: NP_004626 |
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| Catalog # | MBS204901 |
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| Order / More Info | MAPKAPK3, 1-382aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Voncken J.W., et al. (2005) J. Biol. Chem. 280:5178-5187; Mendoza H., et al. (2008) Biochem. J. 409:711-722; |
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