| 产品详情 |
| Edit |   |
|---|
| Product Name | MAPKAPK3, Active, Recombinant, Human |
|---|
| Description | Purity ~90% (SDS-PAGE). MAPKAPK3 has a single potential SH3-binding site in the proline-rich N terminus, a putative ATP-binding site, 2 MAP kinase phosphorylation site motifs, and a putative nuclear localization signal. It shares 72% nucleotide and 75% amino acid identity with MAPKAPK2. MAPKAPK3 was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. MAPKAPK3 is uniquely poised to support luteal maturation through the phosphorylation and activation of the nuclear transcript |
|---|
| Size | 5ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | MAPKAPK3, Active, Recombinant, Human (Active MAPKAPK3, MAPKAPK3, MAPKAPK, human MAPKAPK3, active kinase, active kinases, recombinant MAPKAPK3, recombinant MAPKAPK3 kinase activity assay, protein kinase) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 167909 |
|---|
| Price | |
|---|
| Order / More Info | MAPKAPK3, Active, Recombinant, Human from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|