产品详情 |
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Antigenic Specificity | BAG4 |
Clone | 2G9 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay-Dependent, Western Blot: 1-5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BAG4 Monoclonal Antibody (2G9). The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein |
Immunogen | n/a |
Other Names | BAG-4, SODD; BAG family molecular chaperone regulator 4; BAG-family molecular chaperone regulator-4; bcl-2-associated athanogene 4; silencer of death domains |
Gene, Accession # | Entrez: 9530; Uniprot: O95429 |
Catalog # | MA5-20758 |
Price | |
Order / More Info | BAG4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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