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| Product Name | Akt, Phosphorylated (S473), BioAssay™ ELISA Kit |
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| Description | The serine/threonine kinase Akt, also known as protein kinase B (PKB), is a central player in such diverse cellular processes as glucose uptake, cell cycle progression, and apoptosis. In mammals, three highly homologous members define the Akt family: Akt1 (PKBa), Akt2 (PKBb), and Akt3 (PKBg). Akt1 is the most ubiquitously expressed member, while Akt2 is expressed predominantly in insulin target tissues such as liver, skeletal muscle, and fat. Akt3 is expressed most selectively, in brain and testis. All three Akts share a conserved structure: an amino-terminal pleckstrin homology domain to interact with membrane phosphoinositides; a central kinase domain; and a carboxyl-terminal regulatory domain that contains the hydrophobic motif, a hallmark of members of the AGC kinase superfamily. Akt signaling is activated by receptor tyrosine kinases, B- and T-cell receptors, cytokine receptors, and other mechanisms that activate phosphoinositide 3-kinase (PI 3-K). Active PI 3-K generates the seco |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A1124-95 |
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| Order / More Info | Akt, Phosphorylated (S473), BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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