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| Product Name | Akt, phosphorylated (Thr308) Control Peptide |
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| Description | Control peptide for corresponding antibody A1124-07C Peptide specificity: Human, mouse AKT, also referred to as PKB or Rac, plays a critical role in controlling the balance between survival and apoptosis (1-3). This protein kinase is activated by insulin and various growth and survival factors, and functions in a wortmannin-sensitive pathway involving PI3 kinase (2,3). AKT is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 (4), and by phosphorylation within the carboxy-terminus at Ser473. AKT promotes cell survival by inhibiting apoptosis through its ability to phosphorylate and inactivate several targets, including Bad (5), Forkhead transcription factors (6), c-Raf (7) and caspase-9. PTEN phosphatase is a major negative regulator of the PI3 kinase/AKT signaling pathway (8). LY294002 is a specific PI3 kinase inhibitor (9). One of the essential functions of AKT is the regulation of glycogen synthesis through phosphorylation and inactivation of gly |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A1124-07C1 |
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| Order / More Info | Akt, phosphorylated (Thr308) Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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