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Antigenic Specificity | Ki-67 |
Clone | SolA15 |
Host Species | Rat |
Reactive Species | canine, cynomolgus monkey, human, mouse, nonhuman primate, rat |
Isotype | IgG2a, kappa |
Format | PE-eFluor 610 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.125 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ki-67 Monoclonal Antibody (SolA15), PE-eFluor 610, eBioscience™. Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful |
Immunogen | n/a |
Other Names | antigen identified by monoclonal antibody Ki-67; antigen KI-67; KIA; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2 |
Gene, Accession # | Entrez: 100686578, 102135895, 17345, 291234, 4288; Uniprot: E9PVX6, P46013 |
Catalog # | 61-5698-80 |
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Order / More Info | Ki-67 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 23314004, 23451046, 23455507, 23977372, 25348003, 26188064, 26300228, 26656646, 26949251, 27467948, 27588110, 27695003, 27999749, 28123877, 28218906, 28382040, 29031732 |
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