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Antigenic Specificity | Ki-67 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, cervidae, equine, hamster, human, mouse, nonhuman primate, ovine, porcine, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 1:100, Immunocytochemistry: assay dependent, Immunofluorescence: 0.5-1 µg/mL, Immunohistochemistry - Free Floating: 1:500, Immunohistochemistry (Paraffin): 0.1 - 5 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ki-67 Polyclonal Antibody. Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in |
Immunogen | n/a |
Other Names | RP11-380J17.2, KIA, antigen KI-67; proliferation-related Ki-67 antigen |
Gene, Accession # | Entrez: 100055048, 100686578, 100756884, 101106643, 102164100, 17345, 291234, 4288, 513220; Uniprot: E9PVX6, P46013 |
Catalog # | PA5-19462 |
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Order / More Info | Ki-67 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 21108844, 22542682, 24101915, 25128420, 25288394, 25753731, 25854148, 25920494, 26248280, 26440311, 26515640, 26740489, 26859676, 27049717, 27378170, 28895052, 29398601, 29568419 |
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