产品详情 |
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Antigenic Specificity | Ki-67 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:20 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ki-67 Polyclonal Antibody. Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in |
Immunogen | n/a |
Other Names | antigen KI-67, proliferation-related Ki-67 antigen |
Gene, Accession # | Entrez: 291234, 4288; Uniprot: P46013 |
Catalog # | PA5-16446 |
Price | |
Order / More Info | Ki-67 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 21483788, 22563073, 23593223, 23840792, 23861820, 23936234, 24025971, 24682322, 25263389, 25371072, 25924236, 26228788, 26289340, 26552408, 27064283, 27064446, 27703526, 28749466 |
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