| 产品详情 |
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| Antigenic Specificity | Arginase 1 |
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| Clone | A1exF5 |
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| Host Species | Rat |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a, kappa |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1.0 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Arginase 1 Monoclonal Antibody (A1exF5), APC, eBioscience™. Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle. The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation. By degrading arginine Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production. In both, human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells. In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported. In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macro |
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| Immunogen | n/a |
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| Other Names | AI; ARG1; Liver Arginase; Type 1 Arginase; PGIF; |
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| Gene, Accession # | Entrez: 11846, 383; Uniprot: P05089, Q61176 |
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| Catalog # | 17-3697-80 |
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| Price | |
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| Order / More Info | Arginase 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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