产品详情 |
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Antigenic Specificity | Cyclin E |
Clone | HE12 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | eFluor 660 conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cyclin E Monoclonal Antibody (HE12), eFluor 660, eBioscience™. Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in Cyclin E protein have been implicated as indicators of worse prognosis in various cancers. |
Immunogen | n/a |
Other Names | CCNE |
Gene, Accession # | Entrez: 898; Uniprot: P24864 |
Catalog # | 50-9714-80 |
Price | |
Order / More Info | Cyclin E Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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