| 产品详情 |
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| Antigenic Specificity | Cyclin E |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cyclin E Polyclonal Antibody. Cyclin E1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin E1 forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E1 accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of Cyclin E1 has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumori |
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| Immunogen | n/a |
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| Other Names | G1/S-specific cyclin-E1; CCNE1; CCNE |
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| Gene, Accession # | Entrez: 898; Uniprot: P24864 |
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| Catalog # | PA5-13255 |
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| Price | |
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| Order / More Info | Cyclin E Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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