产品详情 |
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Antigenic Specificity | Cyclin E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): Assay Dependent, Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cyclin E Polyclonal Antibody. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and t |
Immunogen | n/a |
Other Names | CCNE |
Gene, Accession # | Entrez: 12447, 25729, 898; Uniprot: P24864, P39949, Q61457 |
Catalog # | LF-PA0168 |
Price | |
Order / More Info | Cyclin E Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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