产品详情 |
Edit |   |
Antigenic Specificity | Cyclin E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 10 µg/mL, Western Blot: 5-10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cyclin E Polyclonal Antibody. Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post-transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers. |
Immunogen | n/a |
Other Names | G1/S-specific cyclin-E1, cyclin Es, cyclin Et |
Gene, Accession # | Entrez: 12447, 898; Uniprot: P24864, Q61457 |
Catalog # | PA5-16237 |
Price | |
Order / More Info | Cyclin E Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 23680462 |
产品资料 |
|
|