产品名称 Cyclin E Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-16237
产品价格 现货询价,电话:010-67529703
产品规格 500 µL
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityCyclin E
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size500 µL
Concentrationn/a
ApplicationsImmunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1:50, Immunoprecipitation: 10 µg/mL, Western Blot: 5-10 µg/mL
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DescriptionCyclin E Polyclonal Antibody. Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post-transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
Immunogenn/a
Other NamesG1/S-specific cyclin-E1, cyclin Es, cyclin Et
Gene, Accession #Entrez: 12447, 898; Uniprot: P24864, Q61457
Catalog #PA5-16237
Price
Order / More InfoCyclin E Antibody from INVITROGEN ANTIBODIES
Product Specific ReferencesPubMed: 23680462
产品资料