| 产品详情 |
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| Antigenic Specificity | Cyclin E1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:100-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cyclin E1 Polyclonal Antibody. Cyclin E belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumo |
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| Immunogen | n/a |
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| Other Names | CCNE |
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| Gene, Accession # | Entrez: 898; Uniprot: P24864 |
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| Catalog # | IHC-00341 |
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| Price | |
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| Order / More Info | Cyclin E1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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