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| Antigenic Specificity | ERN2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:20-1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ERN2 Polyclonal Antibody. ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells. |
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| Immunogen | n/a |
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| Other Names | Serine/threonine-protein kinase/endoribonuclease IRE2 [Precursor]; Inositol-requiring protein 2; hIRE2p; IRE1b; Ire1-beta; Endoplasmic reticulum-to-nucleus signaling 2; ERN2; IRE2; |
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| Gene, Accession # | Entrez: 10595; Uniprot: Q76MJ5 |
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| Catalog # | PA5-53442 |
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| Price | |
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| Order / More Info | ERN2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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