产品详情 |
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Antigenic Specificity | ERO1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Western Blot: 1:1000-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ERO1L Polyclonal Antibody. ERO1L (endoplasmic oxidoreductin-1-like protein) is localized in ER membrane as peripheral membrane protein on lumenal side, its association with ERP44 being essential for its retention in the ER, and is unique in coupleing oxygen reduction to de novo disulfides formation. ERO1L enzyme is broadly distributed at low levels in several tissues with highest levels in upper digestive tract especially the esophagus, and is stimulated by hypoxia via HIF-signaling. ERO1L generally exists as monomer, but has the ability to function as monomer or homodimer and interacts with PDILT. After translation, ERO1L gets n-glycosylated and the disulphide bonds constitute the redox-active center whereby the Cys-94/Cys-99 disulfide bon |
Immunogen | n/a |
Other Names | ERO1-alpha |
Gene, Accession # | Entrez: 171562, 30001, 50527; Uniprot: Q8R180, Q8R4A1, Q96HE7 |
Catalog # | PA1-46120 |
Price | |
Order / More Info | ERO1L Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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