产品详情 |
Edit |   |
Antigenic Specificity | ERO1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | DyLight 488 conjugate |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:1000-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ERO1L Polyclonal Antibody, DyLight 488. Perhaps the most distinctive feature of protein folding in the ER is the abundance of disulfide bonds that must form during maturation of proteins traveling along the secretory pathway. Formation of disulfide bonds is a redox reaction. Thus, to match the flux of disulfide bonds that exit from the ER by virtue of protein secretion, a flux of oxidizing equivalents into the ER is required. In eukaryotic cells, the essential protein relay supporting this flux, and hence disulfide bond formation, involves endoplasmic reticulum oxidoreductin 1 (Ero1) and protein disulfide isomerase (PDI). The temporal pattern of hypoxic ERO1-L alpha induction is very similar to that of genes triggered by the hypoxia inducib |
Immunogen | n/a |
Other Names | UNQ434/PRO865, ERO1-alpha, ERO1A, ERO1-L, ERO1-L-alpha, ERO1-like protein alpha, endoplasmic oxidoreductin-1-like protein, oxidoreductin-1-L-alpha |
Gene, Accession # | Entrez: 171562, 30001, 50527; Uniprot: Q8R180, Q8R4A1, Q96HE7 |
Catalog # | PA5-22744 |
Price | |
Order / More Info | ERO1L Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|