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| Product Name | Diosmetin |
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| Description | Purity >98%. Diosmetin is a natural O -methylated flavone that is structurally related to luteolin . It reversibly inhibits cytochrome P450 (CYP) isoforms 1A1 and 1B1 in human liver microsomes with Ki values of 89 and 16 nM, respectively. It less potently inhibits CYP2C8 and CYP2C9 (Ki s = 3.1 and 1.7 µM, respectively). While diosmetin inhibits CYP1A1 activity, it increases the transcription of the CYP1A1 gene in MCF-7 cells by activating the aryl hydrocarbon receptor when applied at 5 µM. Diosmetin also inhibits signaling through the stem cell factor receptor, c-Kit, at micromolar concentrations. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, Diosmetol, Luteolin 4'-methyl ester |
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| Gene, Accession, CAS # | CAS: 520-34-3 |
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| Catalog # | LS-H7476 |
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| Price | |
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| Order / More Info | Diosmetin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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