| 产品详情 |
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| Antigenic Specificity | PTPN12 |
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| Clone | BL-5-2F8 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 20 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:20-1:200, Immunohistochemistry: 1:20-1:200, Immunoprecipitation: 20 µL/0.5 mg lysate, Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PTPN12 Recombinant Monoclonal Antibody (BL-5-2F8). The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1 |
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| Immunogen | n/a |
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| Other Names | tcag7.1075, PTP-PEST, PTPG1 |
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| Gene, Accession # | Entrez: 5782; Uniprot: Q05209 |
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| Catalog # | A700-007-T |
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| Price | |
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| Order / More Info | PTPN12 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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