| 产品详情 |
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| Antigenic Specificity | PTPN13 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:25-1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PTPN13 Polyclonal Antibody. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activati |
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| Immunogen | n/a |
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| Other Names | FAS-associated phosphatase 1, FAP-1 |
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| Gene, Accession # | Entrez: 5783; Uniprot: Q12923 |
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| Catalog # | PA5-50660 |
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| Price | |
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| Order / More Info | PTPN13 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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