| 产品详情 |
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| Antigenic Specificity | NTHL1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 10 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NTHL1 Polyclonal Antibody. Oxygen radicals damage chromosonal DNA causing cell death and inducing mutations. Although a major focus of oxidatively damaged DNA has centered on the repair of 8-oxo-G, a number of other damaged DNA sites are created by free-radical attack on DNA. The human NTH1 repair protein is one enzyme that has been shown to act on a large number of these other oxidatively damaged DNA sites.A homologue of E. coli Endonuclease III, NTH is a DNA glycosylase with apurinic/apyrimidinic lyase activity. The NTH protein has broad substrate specificity, including numerous ring saturation and fragmentation products of pyrimidines. Research indicates NTH plays a crucial role in removal of oxidative base lesions in mitochondrial DNA. |
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| Immunogen | n/a |
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| Other Names | Endonuclease III like 1, NTHL 1, OCTS 3 |
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| Gene, Accession # | Entrez: 4913; Uniprot: P78549 |
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| Catalog # | A305-366A-T |
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| Price | |
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| Order / More Info | NTHL1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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