产品详情 |
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Antigenic Specificity | Synphilin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | lyophilized |
Applications | Immunohistochemistry: 1:1000-1:2000, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Synphilin 1 Polyclonal Antibody. Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shares a high level of identity with its human counterpart, particularly in regions containing ankyrin-like motifs and the coiled-coil domain. Expression pattern of synphilin-1 in tissues is similar in both mouse and human. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and also Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. |
Immunogen | n/a |
Other Names | Alpha-synuclein-interacting protein, SNCAIP |
Gene, Accession # | Entrez: 307309, 9627; Uniprot: Q9Y6H5 |
Catalog # | PA1-18270 |
Price | |
Order / More Info | Synphilin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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