| 产品详情 |
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| Antigenic Specificity | SYNPO2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:2500 - 1:5000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SYNPO2 Polyclonal Antibody. SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of signaling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that |
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| Immunogen | n/a |
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| Other Names | genethonin 2; genethonin-2; myopodin; synaptopodin-2 |
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| Gene, Accession # | Entrez: 171024; Uniprot: Q9UMS6 |
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| Catalog # | PA5-67000 |
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| Price | |
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| Order / More Info | SYNPO2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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