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| Antigenic Specificity | SYNPO2L |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay Dependent, Immunofluorescence: 20 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SYNPO2L Polyclonal Antibody. SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development. |
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| Immunogen | n/a |
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| Other Names | synaptopodin 2-like protein |
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| Gene, Accession # | Entrez: 68760, 79933; Uniprot: Q8BWB1, Q9H987 |
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| Catalog # | PA5-21056 |
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| Price | |
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| Order / More Info | SYNPO2L Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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