产品详情 |
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Antigenic Specificity | ZO-3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Western Blot: 0.5-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ZO-3 Polyclonal Antibody. ZO-3 is a member of the membrane associated guanylate kinse (MAGUK) family and are considered tight junction-associated proteins. Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells. ZO-3 is believed to have both structural and signaling roles, and is characteristically defined by three protein-protein interaction modules: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight j |
Immunogen | n/a |
Other Names | ZO-3, ZO3, TJP3 |
Gene, Accession # | Entrez: 27134; Uniprot: O95049 |
Catalog # | 720298 |
Price | |
Order / More Info | ZO-3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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