产品详情 |
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Antigenic Specificity | Ki-67 |
Clone | 4A1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1/200 - 1/1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ki-67 Monoclonal Antibody (4A1). Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fract |
Immunogen | n/a |
Other Names | KIA; Ki-67; MKI67 |
Gene, Accession # | Entrez: 4288; Uniprot: P46013 |
Catalog # | MA5-15525 |
Price | |
Order / More Info | Ki-67 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 22738312, 24743243, 26526579 |
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